1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor used in the remedy of a number of myeloma. Its synthesis or examine is crucial for ensuring the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A vital compound inside the synthesis of imatinib, a drug that targets certain kinds of most cancers, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are typically intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their analyze is essential for optimizing the manufacturing process and making certain large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): 1-AMINO-3-ADAMANTANOL Lapatinib is applied to treat breast cancer, and these intermediates are associated with its production.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Employed in the cure of breast cancer. Different intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers for example ovarian, breast, and lung cancer.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and smaller mobile lung most cancers.
three-Amino-one-hydroxyadamantane 1-BOC-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE (CAS 702-82-nine): This compound is linked to the synthesis of adamantane derivatives, that have a variety of programs, including antiviral properties.
Vildagliptin Intermediates: Used in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is associated with the synthesis of varied gluconic acid derivatives, which might be Utilized in meals, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication utilized to manage kind two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).